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Another Lost World
THIS CONTENT IS NO LONGER BEING UPDATED OR REFUNDED, CONSIDER THIS YOUR PURCHASE OF FUTURE CONTENT.[Regulation of NO synthase in basal conditions and in response to endotoxemia].
We have studied the role of inducible nitric oxide synthase (iNOS) and its substrate L-arginine and several compounds, including non-specific NOS inhibitor L-NAME and 14C-arachidonate release assay, in the regulation of constitutive NOS (cNOS). We found that L-NAME enhanced the LPS-induced activation of cNOS. In contrast, it did not alter the activation of iNOS, the uptake of L-arginine by the endothelial cells, the release of arachidonate from prelabeled cells, or the level of cNOS protein. Our data show that L-NAME increases the LPS-mediated activation of cNOS, but it does not affect the regulation of the iNOS. This suggests that the increase in cNOS activity during endotoxemia is due to a redistribution of NOS isoforms.Q:
Python Script to Transform a CSV File
I am looking for a script in Python, that transforms a CSV file of the form
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